{"id":9555,"date":"2026-07-22T11:45:26","date_gmt":"2026-07-22T09:45:26","guid":{"rendered":"https:\/\/ubc.uu.nl\/?p=9555"},"modified":"2026-07-22T11:45:53","modified_gmt":"2026-07-22T09:45:53","slug":"1700-new-proteins-expand-the-human-proteome","status":"publish","type":"post","link":"https:\/\/ubc.uu.nl\/1700-new-proteins-expand-the-human-proteome\/","title":{"rendered":"1,700 New Proteins Expand the Human Proteome"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"9555\" class=\"elementor elementor-9555\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-57544ac elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"57544ac\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-74db9271\" data-id=\"74db9271\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-665fc20 elementor-widget elementor-widget-text-editor\" data-id=\"665fc20\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div style=\"display: flex; align-items: flex-start; gap: 30px;\"><div style=\"flex: 1; padding: 0; margin: 0;\"><p>Sebastiaan van Heesch and PhD candidate Leron Kok contributed to the discovery of\u00a0<a href=\"https:\/\/mailings.uu.nl\/i\/ArykLDyVVtp9IA2sAzl3PoqLeRccMIp0\">1,700 previously unknown microproteins<\/a>, published in\u00a0<i>Nature<\/i>. By making these proteins accessible through public databases, the researchers are opening new opportunities to study their role in diseases such as childhood cancer and identify future therapeutic targets.\u00a0The discovery also underpins the newly launched <a href=\"https:\/\/mailings.uu.nl\/i\/0tgin3Hd6Z--yTZMn1kmv9O4gOKh35jh\">ORFeus<\/a> training programme, coordinated by Van Heesch, which will train the next generation of researchers to explore the &#8216;dark proteome&#8217;.<\/p><p style=\"margin-top: 15px; margin-bottom: 0;\"><a style=\"font-weight: bold;\" href=\"https:\/\/mailings.uu.nl\/i\/4pJVhNmwfNI1xiAmeRUNqkBitcz53yFd\"><br \/>Read more<br \/><\/a><\/p><\/div><div style=\"width: 250px; margin: 0; padding: 0;\"><p><img decoding=\"async\" style=\"width: 250px; max-width: 100%; height: auto; display: block; margin: 0;\" src=\"https:\/\/mailings.uu.nl\/c\/hOmk1hd6Lhis79grAFKNXg\/media\/UBC-Sebastiaan-van-Heesch-Leron-Kok.jpg\" alt=\"1,700 New Proteins Expand the Human Proteome\" \/><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Sebastiaan van Heesch and PhD candidate Leron Kok contributed to the discovery of\u00a01,700 previously unknown microproteins, published in\u00a0Nature. By making these proteins accessible through public databases, the researchers are opening new opportunities to study their role in diseases such as childhood cancer and identify future therapeutic targets.\u00a0The discovery also underpins the newly launched ORFeus training [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":9522,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_angie_page":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"page_builder":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[27,408,397],"tags":[],"class_list":["post-9555","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-highlights","category-news_freestyle","category-research"],"acf":[],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/ubc.uu.nl\/wp-content\/uploads\/2026\/07\/UBC-Sebastiaan-van-Heesch-Leron-Kok.jpg","_links":{"self":[{"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/posts\/9555","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/users\/94"}],"replies":[{"embeddable":true,"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/comments?post=9555"}],"version-history":[{"count":4,"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/posts\/9555\/revisions"}],"predecessor-version":[{"id":9613,"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/posts\/9555\/revisions\/9613"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/media\/9522"}],"wp:attachment":[{"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/media?parent=9555"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/categories?post=9555"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ubc.uu.nl\/wp-json\/wp\/v2\/tags?post=9555"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}