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Pathogen genomicsPathogen genomics / microbiome
We use bioinformatics to analyze and compare genomes and microbiomes involved in infectious diseases.
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The Group
Pathogen genomics
Pathogen genomics / microbiome
Address / Contact
Heidelberglaan 100
3584 CH
Utrecht
UMC Utrecht
+31 88 75 535 67
G02.265
Research

In microbial genomics, DNA sequencing technologies are employed to analyze hundreds or thousands of bacterial genomes. These data are processed using computational tools to track local and global transmission of bacterial pathogens and to provide information on the acquisition of determinants that contribute to virulence, resistance to antibiotics or other fitness traits.

We also generate and compare targeted microbial community profiling (16S) of the human microbiome in healthy and diseased patients. For higher resolution taxonomic profiling of the human microbiome and to annotate genes and metabolic pathways and to assemble partial to full genomes of microorganisms we use metagenomic data.