Biomedical Genomics

Wouter de Laat

Our Research

Biomedical genomics
The architecture of DNA in the interior of the living cell nucleus is an emerging key contributor to genomic function. Aim of our research is to understand how genome structure influences genome function. We use and develop novel genomics approaches such as 4C technology to identify long-range DNA interactions, study gene regulation within and between mammalian chromosomes and uncover the proteins that dictate the shape of our genome. Besides transcription we study the impact of nuclear architecture on genomic rearrangements. Furthermore, we develop novel strategies to identify and map chromosomal aberrations.

Research Group

Wouter de Laat
Group name: De Laat Lab
Research field: Biomedical Genomics
Department: Hubrecht Institute


Uppsalalaan 8
3584 CT
Building: Hubrecht Building