UBC Seminar: Improving fungal identification from environmental and clinical samples

Jan 20 (16-17) @ TBC, UU.

To show our support to the National Protest 25 November in The Hague: Stop education cuts in NL! The UBC board decided to reschedule the UBC seminar from Monday, November 25 at 16:00 to Monday, January 20, 2025, at 16:00. Big thanks to the speaker Dr. Duong Vu from the Westerdijk Fungal Biodiversity Institute for offering her flexibility. 

Just come without registration. Don’t miss this opportunity to learn more about the work of one of our new PIs and to catch up with other UBCers with a New Year’s toast afterwards!

Improving fungal identification from environmental and clinical samples

Fungi, with an estimated 2-6 million species, represent a vast and diverse group; yet, less than 5% of them have been described. They are essential for maintaining ecosystem health and stability, contributing to nutrient cycling, forming symbiotic relationships, facilitating decomposition, and supporting various other ecological processes. Some fungi are pathogenic and can cause severe diseases in plants, animals, and humans.

Accurate identification of fungi from environmental and clinical samples is crucial for understanding the causes and consequences of environmental changes and for developing appropriate treatments for fungal diseases. This process, however, can be challenging due to the lack of comprehensive reference data and the vast number of environmental samples being generated with the rapid development of sequencing technologies, which requires computational methods that can identify fungi quickly and accurately.

In my talk, I will present the fungal DNA barcode dataset generated at the Westerdijk Institute, which won the Dutch Data Prize in 2022 in the Life Sciences category for fungal identification. Additionally, I will discuss several computational methods, including AI techniques, that we have developed and applied to enhance fungal identification from environmental and clinical samples using DNA barcodes and whole fungal genomes.

There will be a 35-min presentation followed by a 15-min in-depth discussion.

About the speaker

Duong Vu obtained a PhD in Computer Science in 2007 at the University of Amsterdam and is currently working at the Westerdijk Fungal Biodiversity Institute as a research scientist in bioinformatics. Their main research focuses on developing and applying computational techniques for identifying fungal species and dark taxa from environmental and clinical samples, as well as gaining insights into biological processes. The research area includes artificial intelligence (AI), big data clustering, visualization, and development of analysis tools and pipelines for eDNA metabarcoding/metagenomics, genomics, and image data generated from fungal strains preserved in the WI-CBS collection, as well as data available from public repositories.

Location: TBC.

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