Real-Time view of DNA repair

Real-Time view of DNA repair

Tuncay Baubec and Richard Cardoso da Silva have developed a fluorescent probe that lets researchers watch DNA damage and repair unfold in real time inside living cells and even in whole organisms. The tool offers a much clearer view of how cells maintain their genomes and enables experiments that were not possible before. 

Their paper was recently published in Nature Communications:

Engineered chromatin readers track damaged chromatin dynamics in live cells and animals
Richard Cardoso da Silva, Kristeli Eleftheriou, Davide C. Recchia, Vincent Portegijs, Douwe ten Bulte, Niklas Kupfer, Nathalie P. Vroegindeweij-de Wagenaar, Xabier Vergara, Ayoub Ouchene, Sander van den Heuvel, Tuncay Baubec
Nature Communications, 20 November 2025. 


See also the article on the website of the UU